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KMID : 0378019870300070059
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New Medical Journal
1987 Volume.30 No. 7 p.59 ~ p.62
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A Case of Sideroblastic Anemia
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Jung Bong-Soo
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Abstract
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Sideroblastic anemia is characterized, by a) hypochronlic anemia b) ringed sideroblasts in the bone marrow c) increase in the bone marrow in total body iron d) ineffective erythropoiesis.
A defect of heme biosynthesis, which results in intramitochondrial iron storage, is the pathophysiological basis of this anemia.
The authors experienced one case of this sideroblastic anemia in a 7 month-old, female infant. Her chief complaint was dyspnea and pallor for 3 days. Peripheral blood smear showed severe anemia and slight microcytosis and hypochromia. Bone marrow examination showed marked erythroid hyperpla: ia, reversed M:E ratio, and many ringed sideroblasts.
Brief review of related literature was presented.
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